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Mouse PRDM16 (Pr Domain Zinc Finger Protein 16) ELISA Kit
Mouse PRDM16 (Pr Domain Zinc Finger Protein 16) ELISA Kit
The Mouse (PRDM16) Pr Domain Zinc Finger Protein 16 ELISA Kit measures PR domain zinc finger protein 16 in Mouse samples. The plate has been pre-coated with Mouse PRDM16 antibody. PRDM16 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse PRDM16 Antibody is added and binds to PRDM16 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PRDM16 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse PRDM16. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2358Mo
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
5.22 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Epigenetics and Nuclear Signaling
Background
Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs (PubMed:27102484).
Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (PubMed:27102484).
Binds specifically to the PRDI element in the promoter of the beta-interferon gene (By similarity).
Drives the maturation of B-lymphocytes into Ig secreting cells (By similarity).
Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (PubMed:27102484). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
PR domain zinc finger protein 16
Regulatory Status
For Research Use Only
