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Mouse Thrombospondin Type-1 Domain-Containing Protein 1 (THSH1) ELISA Kit
Mouse Thrombospondin Type-1 Domain-Containing Protein 1 (THSH1) ELISA Kit
This ELISA kit is designed to detect Mouse Thrombospondin Type-1 Domain-Containing Protein 1 (Mouse THSH1). The assay plate has been pre-coated with mouse anti-Mouse THSD1 monoclonal antibody. When the sample containing THSD1 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Mouse THSD1 Antibody is added to the wells and binds to THSD1 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Mouse THSD1 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE315
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Mouse
Sensitivity
16.94 pg/mL
Detection Range
62.5-4000 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Cardiovascular, Cell Biology, Tags and Cell Markers
Background
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Thrombospondin type-1 domain-containing protein 1
Regulatory Status
For Research Use Only
