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Rat ACE2 (Angiotensin Converting Enzyme 2) ELISA Kit
Rat ACE2 (Angiotensin Converting Enzyme 2) ELISA Kit
The Rat (ACE2) Angiotensin Converting Enzyme 2 ELISA Kit measures Angiotensin Converting Enzyme 2 in Rat samples. The plate has been pre-coated with Rat ACE2 antibody. ACE2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat ACE2 Antibody is added and binds to ACE2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ACE2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat ACE2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0968Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
0.23 ng/mL
Detection Range
0.5-100 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Microbiology, Cell Biology, Cardiovascular, Enzyme & Kinase
Background
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin I to angiotensin 1-9, a nine-amino acid Peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II. Also removes the C-terminal residue from three other vasoactive Peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin. Also cleaves other biological Peptides, such as apelins, casomorphins and dynorphin A. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Angiotensin Converting Enzyme 2
Regulatory Status
For Research Use Only
