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Rat BCL2L1 (Bcl-2-like Protein 1) ELISA Kit
Rat BCL2L1 (Bcl-2-like Protein 1) ELISA Kit
The Rat (BCL2L1) Bcl-2-like Protein 1 ELISA Kit measures Bcl-2-Like Protein 1 in Rat samples. The plate has been pre-coated with Rat BCL2L1 antibody. BCL2L1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat BCL2L1 Antibody is added and binds to BCL2L1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated BCL2L1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat BCL2L1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1880Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
0.012 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cell Biology, Apoptosis
Background
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion Channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP Synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). Isoform Bcl-X(S) promotes apoptosis. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Bcl-2-Like Protein 1
Regulatory Status
For Research Use Only
