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Rat CGA (Chromogranin-A) ELISA Kit
Rat CGA (Chromogranin-A) ELISA Kit
The Rat (CGA) Chromogranin-A ELISA Kit measures Chromogranin-A in Rat samples. The plate has been pre-coated with Rat CgA antibody. CgA present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat CgA Antibody is added and binds to CgA in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CgA antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat CgA. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0557Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
0.93 ng/mL
Detection Range
2-600 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction, Neuroscience, Cancer, Metabolism
Background
Strongly inhibits glucose induced insulin release from the pancreas.
Catestatin inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.
Serpinin regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation (By similarity).
Serpinin and pGlu-serpinin can enhance both myocardial contractility (inotropy) and relaxation (lusitropy) and this cardio-stimulation requires a beta 1-adrenergic receptor/adenylate cyclase/cAMP/PKA pathway (PubMed:22459152). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Chromogranin-A
Regulatory Status
For Research Use Only
