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Rat CIRBP (Cold-inducible RNA-binding Protein) ELISA Kit
Rat CIRBP (Cold-inducible RNA-binding Protein) ELISA Kit
The Rat (CIRBP) Cold-inducible RNA-binding Protein ELISA Kit measures Cold-inducible RNA-binding protein in Rat samples. The plate has been pre-coated with Rat CIRBP antibody. CIRBP present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat CIRBP Antibody is added and binds to CIRBP in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CIRBP antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat CIRBP. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1332Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
2.47 ng/L
Detection Range
5-1000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Epigenetics and Nuclear Signaling, Cell Biology
Background
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Cold-inducible RNA-binding protein
Regulatory Status
For Research Use Only
