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Rat ER-beta (Estrogen Receptor Beta) ELISA Kit
Rat ER-beta (Estrogen Receptor Beta) ELISA Kit
The Rat (ER-beta) Estrogen Receptor Beta ELISA Kit measures Estrogen Receptor beta in Rat samples. The plate has been pre-coated with Rat ER-beta antibody. ER-beta present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat ER-beta Antibody is added and binds to ER-beta in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ER-beta antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat ER-beta. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1121Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
7.22 ng/L
Detection Range
15-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Epigenetics and Nuclear Signaling, Endocrinology, Hormone Metabolism
Background
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Lacks ligand binding affinity and suppresses ESR1/ER-alpha and ESR2 isoform 1/ER-beta1 mediated transcriptional activation and may act as a dominant negative regulator of estrogen action.
Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain.
Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Estrogen Receptor beta
Regulatory Status
For Research Use Only
