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Rat GRK6 (G Protein-coupled Receptor Kinase 6) ELISA Kit
Rat GRK6 (G Protein-coupled Receptor Kinase 6) ELISA Kit
The Rat (GRK6) G Protein-coupled Receptor Kinase 6 ELISA Kit measures G protein-coupled receptor kinase 6 in Rat samples. The plate has been pre-coated with Rat GRK6 antibody. GRK6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat GRK6 Antibody is added and binds to GRK6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated GRK6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat GRK6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1969Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
9.69 ng/L
Detection Range
20-4500 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction, Enzyme & Kinase
Background
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity).
Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro) (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
G protein-coupled receptor kinase 6
Regulatory Status
For Research Use Only
