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Rat KMO (Kynurenine 3-monooxygenase) ELISA Kit
Rat KMO (Kynurenine 3-monooxygenase) ELISA Kit
The Rat (KMO) Kynurenine 3-monooxygenase ELISA Kit measures Kynurenine 3-Monooxygenase in Rat samples. The plate has been pre-coated with Rat KMO antibody. KMO present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat KMO Antibody is added and binds to KMO in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated KMO antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat KMO. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2127Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
4.42 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Kynurenine 3-Monooxygenase
Regulatory Status
For Research Use Only
