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Rat PAI-1 (Plasminogen Activator Inhibitor 1) ELISA Kit
Rat PAI-1 (Plasminogen Activator Inhibitor 1) ELISA Kit
The Rat (PAI-1) Plasminogen Activator Inhibitor 1 ELISA Kit measures Plasminogen Activator Inhibitor 1 in Rat samples. The plate has been pre-coated with Rat SERPINE1 antibody. SERPINE1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat SERPINE1 Antibody is added and binds to SERPINE1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated SERPINE1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat SERPINE1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0636Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
0.49 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cell Biology
Background
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Plasminogen Activator Inhibitor 1
Regulatory Status
For Research Use Only
