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Rat PRDX6 (Peroxiredoxin 6) ELISA Kit
Rat PRDX6 (Peroxiredoxin 6) ELISA Kit
The Rat (PRDX6) Peroxiredoxin 6 ELISA Kit measures Peroxiredoxin 6 in Rat samples. The plate has been pre-coated with Rat PRDX6 antibody. PRDX6 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat PRDX6 Antibody is added and binds to PRDX6 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PRDX6 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat PRDX6. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1635Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
5.17 ng/L
Detection Range
10.23-3000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction
Background
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed:15004285).
Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides (By similarity).
Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (PubMed:8999971, PubMed:15004285, PubMed:17652308).
These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (By similarity).
Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (By similarity).
Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (PubMed:26830860).
Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Peroxiredoxin 6
Regulatory Status
For Research Use Only
