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Rat SMAD1 (Mothers Against Decapentaplegic Homolog 1) ELISA Kit
Rat SMAD1 (Mothers Against Decapentaplegic Homolog 1) ELISA Kit
The Rat (SMAD1) Mothers Against Decapentaplegic Homolog 1 ELISA Kit measures Mothers against decapentaplegic homolog 1 in Rat samples. The plate has been pre-coated with Rat Smad1 antibody. Smad1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat Smad1 Antibody is added and binds to Smad1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated Smad1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat Smad1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0077Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
4.1 ng/L
Detection Range
8.12-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). Has been shown to be also activated by TGF-beta (transforming growth factor) type I receptor kinase in rat intestinal epithelial cells (IEC 4-1). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (By similarity). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Mothers against decapentaplegic homolog 1
Regulatory Status
For Research Use Only
