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Rat TIMP-1 (Tissue Inhibitors of Metalloproteinase 1) ELISA Kit
Rat TIMP-1 (Tissue Inhibitors of Metalloproteinase 1) ELISA Kit
The Rat (TIMP-1) Tissue Inhibitors of Metalloproteinase 1 ELISA Kit measures Tissue Inhibitors of Metalloproteinase 1 in Rat samples. The plate has been pre-coated with Rat TIMP1 antibody. TIMP1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat TIMP1 Antibody is added and binds to TIMP1 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TIMP1 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat TIMP1. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E0322Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
0.02 ng/mL
Detection Range
0.05-10 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cardiovascular
Background
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Tissue Inhibitors of Metalloproteinase 1
Regulatory Status
For Research Use Only
