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Rat TPA (Tissue-type Plasminogen Activator) ELISA Kit
Rat TPA (Tissue-type Plasminogen Activator) ELISA Kit
The Rat (TPA) Tissue-type Plasminogen Activator ELISA Kit measures Tissue-Type Plasminogen Activator in Rat samples. The plate has been pre-coated with Rat PLAT antibody. PLAT present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat PLAT Antibody is added and binds to PLAT in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated PLAT antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat PLAT. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E1758Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
/
per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
0.04 ng/mL
Detection Range
0.1-40 ng/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Research Areas
Cardiovascular
Background
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (PubMed: 1515147). Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
Tissue-Type Plasminogen Activator
Regulatory Status
For Research Use Only
