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Rat UGT2B7 (Udp-Glucuronosyltransferase 2B7) ELISA Kit
Rat UGT2B7 (Udp-Glucuronosyltransferase 2B7) ELISA Kit
The Rat (UGT2B7) Udp-Glucuronosyltransferase 2B7 ELISA Kit measures UDP-glucuronosyltransferase 2B7 in Rat samples. The plate has been pre-coated with Rat UGT2B7 antibody. UGT2B7 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat UGT2B7 Antibody is added and binds to UGT2B7 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated UGT2B7 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat UGT2B7. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Catalog No:
E2314Ra
Regular price
$595.00 USD
Regular price
$458.00 USD
Sale price
$595.00 USD
Unit price
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per
2.5 weeks
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Product Details
Species Reactivity
Rat
Sensitivity
4.66 ng/L
Detection Range
10-2000 ng/L
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
1.5 hour(s)
Background
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol, estriol,catechol estrogens). Also regulates the levels of retinoic acid, a major metabolite of vitamin A involved in apoptosis, cellular growth and differentiation, and embryonic development. Contributes to bile acid (BA) detoxification by catalyzing the glucuronidation of BA substrates, which are natural detergents for dietary lipids absorption. Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist losartan, caderastan and zolarsatan, drugs which can inhibit the effect of angiotensin II. Also metabolizes mycophenolate, an immunosuppressive agent. Source: UniProt Consortium (2025)
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
2-8C
Analyte
UDP-glucuronosyltransferase 2B7
Regulatory Status
For Research Use Only
