1
/
of
2
Recombinant Human PRKAR1A (C-6His)
Recombinant Human PRKAR1A (C-6His)
Recombinant Human cAMP-dependent Protein Kinase Regulatory Type I-alpha is produced by our Mammalian expression system and the target gene encoding Glu2-Val381 is expressed with a 6His tag at the C-terminus.
Catalog No:
EPT222
Regular price
$199.00 USD
Regular price
Sale price
$199.00 USD
Unit price
/
per
Couldn't load pickup availability
Product Details
Accession
P10644
Molecular Weight
44 KDa
Apparent Molecular Weight
45-55 KDa, reducing conditions
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Expression Host
Mammalian
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping Condition
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed in the Storage field.
Storage Condition and Shelf Life
Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.
Background
cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylationof different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids.
Analyte
PRKAR1A
Regulatory Status
For Research Use Only
