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Rhesus Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii ELISA Kit
Rhesus Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii ELISA Kit
This ELISA kit is designed to detect Rhesus Low Affinity Immunoglobulin Gamma Fc Region Receptor III. The assay plate has been pre-coated with mouse anti-Rhesus CD16 monoclonal antibody. When the sample containing CD16 is added to the plate, it binds to the antibodies coated on the wells. Then, a horseradish peroxidase conjugated mouse anti-Rhesus CD16 Antibody is added to the wells and binds to CD16 in the sample. After washing the wells, substrate solutions are added, and the color intensity is directly proportional to the amount of Rhesus CD16 present. The reaction is stopped by adding an acidic stop solution, and the absorbance is measured at 450 nm.
Catalog No:
BPE365
Regular price
$754.00 USD
Regular price
$580.00 USD
Sale price
$754.00 USD
Unit price
/
per
2 weeks
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Product Details
Species Reactivity
Rhesus
Sensitivity
2.96 pg/mL
Detection Range
12.5-800 pg/mL
Sample Type
Serum, plasma, cell culture supernates
Incubation(s)
3.5 hour(s)
Research Areas
Immunology, Stem cells
Background
Signal transduction，Immunology bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
Shipping Condition
Shipped on cold gel packs.
Storage Condition and Shelf Life
This product can be stored at 2-8C.
Analyte
Low affinity immunoglobulin gamma Fc region receptor III
Regulatory Status
For Research Use Only
